What We Offer
A platform to product approach for cell modulation in manufacturing
CELMO™: A CELLULAR WORLD MODEL
One Foundation. Multiple functional layers for smarter biomanufacturing
CelMo™, our AI-driven Virtual Cell platform, is the foundation layer of ChemT’s innovation. By integrating manufacturing conditions, cell profiles, perturbation data, and multi-omics inputs, CelMo™ models cell states and predicts how cells respond to process, genetic, and molecular changes. The platform is trained on over 10 billion proprietary sequencing reads and supported by wet-lab validation.
Built on this foundation are functional layers for specific CMC needs, including cell-focused target discovery, de novo small molecule design to modulate cells & optimize biomanufacturing and AI agents for cell engineering.
WHY CHOOSE OUR PLATFORM
Lesser Trial & Error: Guide cell line and process development with more targeted experiments, helping teams converge on a stable process faster.
Clearer decision making: Connect cell behaviour to underlying mechanisms, bringing a biology lens to engineering-driven process development so teams understand not just what works, but why.
Faster root-cause identification: Identify early failure signals in manufacturing and pinpoint likely drivers of viability or product quality issues, with prioritized actions to resolve them.
CHO Cell Applications
We are applying CelMo™ to CHO cells, the workhorse of antibody and protein production, to optimize cell engineering & bioprocess performance. Our solutions are aimed at enhancing cell expansion and productivity in bioreactors. While CHO cells produce over 70% of biologics in a market exceeding $400B, manufacturing remains costly, complex, and inefficient. The challenge extends beyond low titer — CHO teams often lack visibility into the cell-state changes that drive productivity, stress, viability and consistency.
Our CHO program is designed to:
T cell ApplicationS
Chemplify™ is our flagship small molecule for T cell therapy manufacturing, targeting a novel pathway discovered through CelMo™. It boosts T cell expansion and promotes a younger, healthier cell state through a novel anti-senescence mechanism, addressing manufacturing bottlenecks while opening a new way to understand T cell biology.
Chemplify demonstrates the ability to:
Chemplify™ , is now commercially available for T cell therapeutic manufacturing.
CELMO™: BEYOND A SINGLE CELL TYPE
In addition to CHO & T cells, we see strong potential in areas such as stem cells, NK cells, and HEK cells, where precise control over cell state and function can unlock meaningful advances. By applying our AI-driven approach across diverse cellular systems, we aim to create new opportunities in therapeutic development, regenerative medicine, and next-generation biomanufacturing.
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